邢唷 > . 0 - 欹 '` 餜 h! bjbjLULU 2$ .? .? ~ , < < < < < < < v T 8
>
>
>
>
>
$ h @ f C Q <
C < < >
>
< >
< >
< < >
2
怶見=溗 0 " <
C C
P d r < < < < < <
E f f e c t s o f t r e a t m e n t w i t h c a r n i t i n e s i n i n f e r t i l e p a t i e n t s w i t h p r o s t a t o - v e s i c u l o - e p i d i d y m i t i s .
YT鎉薳墍眡鎉薳墍眡 + YNp戞]薳墍眡 (W籰梪MRRz伨|蔞D杶w巔
N瞼莡舥篘剉梪He
V i c a r i E , C a l o g e r o A E .
0齎篘{| u杒Bg譥 0H u m R e p r o d 2 0 0 1 ; 1 6 ( 1 1 ) : 2 3 3 8 - 4 2 .
B A C K G R O U N D : W e h a v e r e c e n t l y s h o w n t h a t p a t i e n ts with prostato-vesiculoepididymitis (PVE) have a greater reactive oxygen species (ROS) overproduction than patients with prostatitis or prostato-vesiculitis. Since this biochemical stress persists even after treatment with antimicrobials, it may relate to an imbalance between pro- and anti-oxidant factors at the epididymal level.
虁ofb霳 g褟翄f哊MRRz
緗蔞
D杶w巔P V E 剉舥篘詋MRUS瘇剉Rz亷pbMRRz
緗蔞巔舥篘齹 u鬴Y剉;m'`'lGr璭R O S 0sS縊(WO(u梑虄BR籰梪KNT 購蛓 uirSf[ir(峗NO N魐c韣X[(W 僛颯齹黐魜(WD杶w4ls^
N剉睳'l'`孴梑'l'`郪P[KN魰剉1Ya0
M E T H O D S : T o e v a l u a t e t h e e f f e c t s o f a n t i o x i d a n t t r e a t m e n t o f p a t i e n t s w i t h P V E , w h e t h e r i n t h e p r e s e n c e o r a b s e n c e o f p r o o x i d a n t f a c t o rs, abacterial PVE infertile patients with normal (< 1 x 106/ml, group A, n =34) or abnormal (> 1 x 106/ml, group B, n = 20) seminal white blood cell (WBC) concentrations received carnitines (L-carnitine 1 g and acetyl- carnitine 0.5 g twice/day) for 3 months followed by a wash-out period of 3 months. Semen parameters, ROS production and pregnancy outcome were evalsuated before, during and following carnitine treatment.
筫誰:N膵0OO(u梑'lSBR籰梪P V E 舥篘剉He済 b霳\^椘~虄'`P V E 剉舥篘
N/f&TX[(W睳'l郪 }0 cgq諲霳緗瞞}v苸迉W B C Sm/fck8^:Nh芉R:N$N膥 A ck8^膥 n = 3 4 緗瞞-N剉W B C < 1 x 1 0 6 / m l B 膥/f_8^膥 n = 2 0 緗瞞-N剉W B C > 1 x 1 0 6 / m l 0舥篘
g(u
YT鎉薳墍眡鎉薳墍眡 蟢!k1 g 錘蔛YNp戞]薳墍眡 蟢!k0 . 5 g 蟢)Y$N!k
g(u3 *Ng 6qT\P(u3 *Ng0(W籰梪KNMR0 g魰孴KNTR+R鵞緗P[(嵪懧Spe0R O S upe蠎錘蔛/f&T `U[蹚L埨hKm0
R E S U L T S : C a r n i t i n e s L N P ` b v x
; < f g
( * 2 F 蹯蹯犰葚胸休禽慷凯犊斂斂嫮~叇叇叇厏叇潶潶
h+" H*KH
h+" KH h+" CJ KH o(h+" CJ H*KH h+" KH \乷(
h+" KH o(h+" 5並H o( h+" 5丆J KH h+" CJ KH h+" OJ QJ o(h+" OJ QJ h+" o(h+" h+" 5丆J KH o( h+" 5丆J KH h+" 5丆J KH o(1 N O f ! ! ! ! ! ! ! ! $! &! (! $ a$ ! f! F P ` h f l
! ! ! ! ! ! ! ! ! "! *! 8! f NM/f芠R鴙sQ剉 sS縊(W\P(u
YT鎉薳墍眡T剉3 *Ng匭 R O S 剉 u_N N魐軴c@wM朜O剉縍`0鵞嶯B 膥舥篘eg矉
YT鎉薳墍眡臢衏貧哊b;m緗P[剉~vR詋緗P[pe蠎 0\P(u鎉薳墍眡剉3 *Ng匭 A 膥舥篘剉 `U[噑f>f貧嶯B 膥舥篘剉 `U[噑 1 1 . 7 4 / 3 4 詋0 0
C O N C L U S I O N : T h e s e r e s u l t s i n d i c a t e t h a t c a r n i t i n e s a r e o n l y a n e f f e c t i v e t r e a t m e n t i n p a t i e n t s w i t h a b a c t e r i a l P V E a n d e l e v a t e d R O S p r o d u c t i o n w h e n s e m i n a l W B C c o n c e n t r a t i o n i s n o r m a l .
觺簨購汵觺済hf鵞嶯緗P[}v苸迉W B C Smck8^臽礠 N剉^椘~虄'`P V E 孴 uR O S 儚Y剉舥篘eg魦
YT鎉薳墍眡鎉薳墍眡 + YNp戞]薳墍眡 /f N蛓 gHe剉籰梪筫誰0
P R O X E E D T M 'k鹼Rf[/gJTKN踁
(! *! R! T! V! X! Z! \! ^! `! b! d! f! h! $a$
0 182P 皞. 捌A!皧"皧#5$慅% 靶靶 愋 J @ J ck噀 $1$ a$ CJ KH _HaJ mH nHsH tH $ A $ 貫祂=刉[SO F i@ F nf恏-->